RNA Details
Disease Name
renal interstitial fibrosis
Tissue
kidney
RNA Symbol
mir-29b-2
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
RT-PCR;western blot;histology
Target
NA
Pathway
PI3K-AKT SIGNALING PATHWAY
PubMed ID
Title
microRNA-29b prevents renal fibrosis by attenuating renal tubular epithelial cell-mesenchymal transition through targeting the PI3K/AKT pathway
Year
2021
Function
MiR-29b significantly prevented tubulointerstitial injury in mouse model of unilateral ureteral obstruction (UUO) by attenuating renal tubular epithelial cell-mesenchymal transition via repressing PI3K/AKT signaling pathway.